Comments on: It’s Clickalicious and Web-Two-Zeroey! http://www.coronene.com/blog/?p=1165 A chemistry blog about organic materials, nanocrap, life in the lab and kittens Tue, 07 Sep 2010 20:43:33 +0000 http://wordpress.org/?v=2.9 hourly 1 By: excimer http://www.coronene.com/blog/?p=1165&cpage=1#comment-8869 excimer Mon, 07 Dec 2009 00:29:00 +0000 http://www.coronene.com/blog/?p=1165#comment-8869 well, you know. Engineers are all about efficiency. Less time in the lab = more time in the bar. Work smarter, not harder. Most organic chemists do not have this mentality. well, you know. Engineers are all about efficiency. Less time in the lab = more time in the bar. Work smarter, not harder. Most organic chemists do not have this mentality.

]]> By: OrganicOverdose http://www.coronene.com/blog/?p=1165&cpage=1#comment-8868 OrganicOverdose Sun, 06 Dec 2009 23:50:57 +0000 http://www.coronene.com/blog/?p=1165#comment-8868 I think you mistook my post comment about coffee earlier. I have no problems with Chemists drinking coffee. I have a problem with biologists that every time I see them it is with a coffee in hand or in a cafe drinking coffee. It was more of a reference to how much spare time they have than a slander on the coffee drinkers of the world. Similarly Engie's are too often in the pub, I love beer but don't have as much time as time to drink it. I think you mistook my post comment about coffee earlier. I have no problems with Chemists drinking coffee. I have a problem with biologists that every time I see them it is with a coffee in hand or in a cafe drinking coffee. It was more of a reference to how much spare time they have than a slander on the coffee drinkers of the world. Similarly Engie’s are too often in the pub, I love beer but don’t have as much time as time to drink it.

]]> By: Ψ*Ψ http://www.coronene.com/blog/?p=1165&cpage=1#comment-8867 Ψ*Ψ Sun, 06 Dec 2009 23:06:55 +0000 http://www.coronene.com/blog/?p=1165#comment-8867 Of course we're supposed to drink coffee. Coffee is a gift from the caffeine gods. They become angry if we reject their blessings. Of course we’re supposed to drink coffee. Coffee is a gift from the caffeine gods. They become angry if we reject their blessings.

]]> By: Dennis http://www.coronene.com/blog/?p=1165&cpage=1#comment-8866 Dennis Sun, 06 Dec 2009 19:22:11 +0000 http://www.coronene.com/blog/?p=1165#comment-8866 Wait, chemists aren't supposed to drink coffee? Huh? Wait, chemists aren’t supposed to drink coffee? Huh?

]]> By: LiqC http://www.coronene.com/blog/?p=1165&cpage=1#comment-8860 LiqC Sat, 05 Dec 2009 18:16:12 +0000 http://www.coronene.com/blog/?p=1165#comment-8860 I can't wait know why do you have to use such a perverted method to make methyl amide. Well, take care. It's not too bad. I've seen people who handled grams of pentaerythtryl tetraazide. Symmetry makes a good stabilizer. Triazidopentaerythritol is sitting in our freezer as a solution in 1 L of ether with unknown concentration, that scares me more. I can’t wait know why do you have to use such a perverted method to make methyl amide.

Well, take care. It’s not too bad. I’ve seen people who handled grams of pentaerythtryl tetraazide. Symmetry makes a good stabilizer. Triazidopentaerythritol is sitting in our freezer as a solution in 1 L of ether with unknown concentration, that scares me more.

]]> By: milkshake http://www.coronene.com/blog/?p=1165&cpage=1#comment-8859 milkshake Sat, 05 Dec 2009 13:49:33 +0000 http://www.coronene.com/blog/?p=1165#comment-8859 Process scale-up: maybe one could do a concentrated click on water, with some lazy copper source like Cu2O and sonication. Water soaks up lots of heat. I think the more unpleasant part is working with large quantities of some low-MW azide, but many times these can be easily generated and handled as solutions. I am contemplating myself working with methyl azide soon, for Aube-Schmidt reaction. (I will report on the size of the resulting hole) Process scale-up: maybe one could do a concentrated click on water, with some lazy copper source like Cu2O and sonication. Water soaks up lots of heat. I think the more unpleasant part is working with large quantities of some low-MW azide, but many times these can be easily generated and handled as solutions.

I am contemplating myself working with methyl azide soon, for Aube-Schmidt reaction. (I will report on the size of the resulting hole)

]]> By: excimer http://www.coronene.com/blog/?p=1165&cpage=1#comment-8847 excimer Sat, 05 Dec 2009 01:25:34 +0000 http://www.coronene.com/blog/?p=1165#comment-8847 Wow. This is like Uncle Al without the high IQ. Is this what the rest of the internet has to put up with? Wow. This is like Uncle Al without the high IQ. Is this what the rest of the internet has to put up with?

]]> By: LiqC http://www.coronene.com/blog/?p=1165&cpage=1#comment-8846 LiqC Sat, 05 Dec 2009 00:11:10 +0000 http://www.coronene.com/blog/?p=1165#comment-8846 Please do us a favor, report your findings in a proper manner. Please do us a favor, report your findings in a proper manner.

]]> By: LiqC http://www.coronene.com/blog/?p=1165&cpage=1#comment-8845 LiqC Sat, 05 Dec 2009 00:06:01 +0000 http://www.coronene.com/blog/?p=1165#comment-8845 The concentrated click blows up because of the energy within a triple bond and three nitrogens is released in one fell swoop. Higher copper (and silver) acetylides are quite benign. It's all been done. The concentrated click blows up because of the energy within a triple bond and three nitrogens is released in one fell swoop. Higher copper (and silver) acetylides are quite benign.

It’s all been done.

]]> By: LiqC http://www.coronene.com/blog/?p=1165&cpage=1#comment-8844 LiqC Sat, 05 Dec 2009 00:01:31 +0000 http://www.coronene.com/blog/?p=1165#comment-8844 Fixed. It's a paper from Roche about improved synthesis of Tamiflu from shikimic acid. Fixed. It’s a paper from Roche about improved synthesis of Tamiflu from shikimic acid.

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